Recent publications:
Click on reference for PubMed index

Tarchini B, Duboule D. (2006). Control of Hoxd genes' collinearity during early limb development. Dev Cell 10, 93-103.

Stern CD, Charite J, Deschamps J, Duboule D, Durston AJ, Kmita M, Nicolas JF, Palmeirim I, Smith JC, Wolpert L. (2006). Head-tail patterning of the vertebrate embryo: one, two or many unresolved problems?. Int J Dev Biol 50, 3-15.

Cobb J, Dierich A, Huss-Garcia Y, Duboule D. (2006). A mouse model for human short-stature syndromes identifies Shox2 as an upstream regulator of Runx2 during long-bone development.. Proc Natl Acad Sci U S A 103, 4511-5.

Cobb, J. and Duboule, D. (2005). Comparative analysis of genes downstream of the Hoxd cluster in developing digits and external genitalia. Development 132, 3055-3067.

Spitz, F. and Duboule, D. (2005). Developmental biology: reproduction in clusters. Nature 434, 715-716.

Spitz, F., Herkenne, C., Morris, M.A. and Duboule, D. (2005). Inversion-induced disruption of the Hoxd cluster leads to the partition of regulatory landscapes. Nat Genet 37, 889-893.

Kmita, M., Tarchini, B., Zakany, J., Logan, M., Tabin, C.J. and Duboule, D. (2005). Early developmental arrest of mammalian limbs lacking HoxA/HoxD gene function. Nature 435, 1113-1116.

Tarchini B, Huynh TH, Cox GA, Duboule D. (2005). HoxD cluster scanning deletions identify multiple defects leading to paralysis in the mouse mutant Ironside. Genes Dev. 19, 2862-76.

Spitz F, Herkenne C, Hinard C, Duboule D. (2005). [A STRING lifts the veil on the mechanisms controlling Hox genes expression.] French. Med Sci (Paris) 22, 14-6.

Cobb, J. and Duboule, D. (2004). Tracing microRNA patterns in mice. Nat Genet 36, 1033-1034.

Zakany, J., Kmita, M. and Duboule, D. (2004) A dual role for Hox genes in limb anterior-posterior asymmetry. Science 304, 1669-72.

Monge, I., Kondo, T. & Duboule, D. (2003) An enhancer-titration effect induces digit-specific regulatory alleles of the HoxD cluster. Dev Biol 256, 212-20.

Spitz, F., Gonzalez, F. and Duboule, D. (2003) A global control region defines a chromosomal regulatory landscape containing the HoxD cluster. Cell 113, 405-17.

Kmita, M. and Duboule, D. (2203) Organizing axes in time and space; 25 years of colinear tinkering. Science 301, 331-3.

Duboule, D. (2002) Making progress with limb models. Nature 418, 492-3.

Kmita, M., Tarchini, B., Duboule, D. and Herault, Y. (2002) Evolutionary conserved sequences are required for the insulation of the vertebrate Hoxd complex in neural cells. Development 129, 5521-8.

Kmita, M., Fraudeau, N., Herault, Y. and Duboule, D. (2002) Serial deletions and duplications suggest a mechanism for the collinearity of Hoxd genes in limbs. Nature 420, 145-50.

Herault, Y., Kmita, M., Sawaya, C. C. and Duboule, D. (2002) A nested deletion approach to generate Cre deleter mice with progressive Hox profiles. Int J Dev Biol 46, 185-91.

Spitz F, Gonzalez F, Peichel C, Vogt TF, Duboule D, Zakany J. (2001) Large scale transgenic and cluster deletion analysis of the HoxD complex separate an ancestral regulatory module from evolutionary innovations. Genes Dev 15, 2209-14.

Zakany, J., Kmita, M., Alarcon, P., de la Pompa, J. L. and Duboule, D. (2001) Localized and transient transcription of Hox genes suggests a link between patterning and the segmentation clock. Cell 106, 207-17.

 

 

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